Guidance on the assessment of iMCD for pathologists

STEP 3:
Histopathological subtyping

Histopathological subtypes of iMCD are useful in building a complete picture of diagnosis, but their clinical relevance remains uncertain. Please see below for guidance on how to identify subtypes.

Diagram showing how to diagnose subtypes of iMCD

Histopathological subtypes

Hypervascular pathology
Mixed pathology
Plasmacytic pathology

Additional guidance

STEP 2

Abbreviations

FDC, follicular dendritic cell; iMCD, idiopathic Multicentric Castleman Disease.

This tool has been funded and produced by Recordati Rare Diseases (RRD). All images have been provided by an international panel of expert pathologists.
The concept, functionality and expert guidance found within this tool has also been developed with the support of expert pathologists.

Prescribing Information

Adverse events should be reported. (UK) Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/. (Ireland) Healthcare professionals are requested to report suspected adverse reactions to HPRA via their website https://www.hpra.ie/. Adverse events should also be reported to Recordati UK Ltd by telephone: +44 (0)1491 414 333 or email: RRDpharmacovigilance@recordati.com.

Clinician - Suspected CD/ iMCD

Pathologist

Clinician - Confirmed CD/ iMCD

Guidance on the assessment of iMCD for pathologists

STEP 3:
Histopathological subtyping

Histopathological subtypes

Guidance on the assessment of iMCD for pathologists

STEP 3: Histopathological subtyping

Histopathological subtypes

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STEP 3:
Histopathological subtyping