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Guidance on the assessment of iMCD for pathologists

HYPERPLASTIC GERMINAL CENTRES

Grade 0
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Grade 3
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STEP 1

This tool has been funded and produced by Recordati Rare Diseases (RRD). All images have been provided by an international panel of expert pathologists.
The concept, functionality and expert guidance found within this tool has also been developed with the support of expert pathologists.

Prescribing Information
Adverse events should be reported. (UK) Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/. (Ireland) Healthcare professionals are requested to report suspected adverse reactions to HPRA via their website https://www.hpra.ie/. Adverse events should also be reported to Recordati UK Ltd by telephone: +44 (0)1491 414 333 or email: RRDpharmacovigilance@recordati.com.

IE-SYL-0103
May 2025

This website is developed by Recordati Rare Diseases (RRD) and is intended for use by healthcare professionals only.
For more information, please contact us at: Email: RRDUnitedKingdominfo@recordati.com Mailing address: Recordati UK Ltd, Breakspear Park, Breakspear Way, Hemel Hempstead HP2 4TZ, United Kingdom
Company reg no: 09329429.
  • H&E

EXPERT GUIDANCE

Hyperplastic GCs: Grade 3

This lymph node shows a prominent follicular hyperplasia, containing numerous secondary GCs.

Abbreviations

GCs, geminal centres; H&E, hematoxylin and eosin.

This tool has been funded and produced by Recordati Rare Diseases (RRD). All images have been provided by an international panel of expert pathologists. The concept, functionality and expert guidance found within this tool has also been developed with the support of expert pathologists.

  • H&E

EXPERT GUIDANCE

Hyperplastic GCs: Grade 0

This lymph node shows a compartimentalisation with a prominent paracortical area and some reactive GCs.

Abbreviations

GCs, geminal centres; H&E, hematoxylin and eosin.

This tool has been funded and produced by Recordati Rare Diseases (RRD). All images have been provided by an international panel of expert pathologists. The concept, functionality and expert guidance found within this tool has also been developed with the support of expert pathologists.

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